{"@context":"https://schema.org","@type":"ScholarlyArticle","headline":"Long-term habitual physical activity and risk of mortality and long-term care insurance certification in cancer survivors: a prospective cohort study in the LIFE study, Japan.","author":[{"@type":"Person","name":"Kiyomasa Nakatsuka"},{"@type":"Person","name":"Rei Ono"},{"@type":"Person","name":"Megumi Maeda"},{"@type":"Person","name":"Fumiko Murata"},{"@type":"Person","name":"Kunihiro Nishimura"},{"@type":"Person","name":"Haruhisa Fukuda"}],"datePublished":"2026","isPartOf":{"@type":"Periodical","name":"BMJ open"},"identifier":"https://doi.org/10.1136/bmjopen-2025-104102","description":"\n Objectives\n This study aimed to investigate the effects of long-term and habitual physical activity on mortality and long-term care insurance (LTCI) certification among cancer survivors using a population database.\n \n \n Design\n 5-year retrospective study.\n \n \n Setting\n 13 Japanese municipalities participated in the Longevity Improvement & Fair Evidence study.\n \n \n Participants\n Among 471 511 participants who underwent health check-ups, 39 435 met the following eligible criteria: documented in the cancer claims database without a suspected diagnosis and participated in a health check-up at least once in a 12-month period, had no missing exercise data and had already been certified for LTCI.\n \n \n Main outcome measures\n Outcomes were new LTCI certification and all-cause mortality. LTCI certification was assigned by a trained local government official through a systematic process (involving various items—physical function, daily activity function, cognitive function, behavioural disorders, adjustment to social life and daily use of medical services—as well as overall consideration of computer-based and specialist team assessments), and the LTCI severity level correlates with the Barthel index. LTCI certification reflects some impairment in activities of daily living. All-cause mortality was defined based on claims data.\n \n \n Results\n Three physical activity categories, ‘exercise and walking’, ‘exercise or walking’ and ‘no physical activity’, were used. Among survivors aged 65–74 years, the ‘no physical activity’ group had a higher risk of mortality and LTCI certification than the ‘exercise and walking’ group (adjusted model HR: 1.72, 95% CI 1.52 to 1.94). Among survivors aged ≥75 years, the low physical activity groups had a higher risk of mortality and LTCI certification than the ‘exercise and walking’ group (adjusted model: ‘exercise or walking’, HR: 1.51, 95% CI 1.29 to 1.85; ‘no physical activity’, HR: 1.66, 95% CI 1.43 to 1.92). The effects of physical activity differed according to cancer type.\n \n \n Conclusions\n Habitual physical activity had positive effects on cancer survivors. These effects differed according to age and cancer type.\n ","url":"https://innscience.ca/en/community/literature/doi_10_1136_bmjopen_2025_104102"}