The embodiment of the invention provides a liquid cooling system control method and system, and belongs to the technical field of equipment temperature control. The method is applied to liquid cooling system control of refining heating furnace monitoring equipment and comprises the steps that real-time operation information of a refining heating furnace is collected, and all working conditions of the refining heating furnace are simulated based on the real-time operation information; based on the simulated working condition, determining operation state information of each monitoring device; based on the operation state information, generating an adjustment rule of the liquid cooling system corresponding to each monitoring device through a fuzzy control rule; and adjusting the operation state of each liquid cooling system based on the adjustment rule. According to the scheme, the problems that an existing liquid cooling system control scheme of refining heating furnace monitoring equipment cannot be suitable for the hearth working environment and the refined control performance is poor are solved.