The invention relates to the field of adhesives, in particular to a low-temperature fast-curing adhesive, a preparation method thereof and a screen printing plate. The low-temperature fast curing adhesive provided by the invention is prepared from the following raw materials: polyamide-imide, epoxy resin, an epoxy resin reactive diluent, a curing agent accelerator, a latent curing agent, a low-temperature curing agent, a defoaming agent and a solvent. The adhesive prepared by the preparation method disclosed by the invention has relatively low thermocuring temperature, and can be cured at the temperature of 120-130 DEG C, so that the energy consumption in the production process is effectively reduced, and the production safety is improved; and the product has high peel strength, and the peel strength is 8N/cm or above.