Exosome Packaging Of Nucleic Acids


Exosome Packaging Of Nucleic Acids




Status: draft

26 Aug 2021
  • method
  • cell
  • nucleic
  • acid
  • interest
  • provided

A method for preparing exosomes or exosome-like vesicles packaged with a nucleic acid of interest is provided. In certain embodiments, the method may comprise: introducing into an exosome-producing cell a nucleic acid construct comprising the nucleic acid sequence of interest incorporated in a pre-miR-451 structural mimic, and allowing the cell to produce exosomes. Nucleic acid constructs, compositions, and uses thereof are also provided.

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