{"@context":"https://schema.org","@type":"ScholarlyArticle","headline":"A Telehealth-Based Behavioral Intervention for Cancer-Related Cognitive Decline in Older Adults Undergoing Systemic Therapy for Breast Cancer: Development and Usability Testing.","author":[{"@type":"Person","name":"J MacLaren Kelly"},{"@type":"Person","name":"Lucia Berkhof"},{"@type":"Person","name":"Oscar Y Franco-Rocha"},{"@type":"Person","name":"Lewis Mustian"},{"@type":"Person","name":"Valerie Targia"},{"@type":"Person","name":"Jessica Bauer"},{"@type":"Person","name":"Jessica Mortimer"},{"@type":"Person","name":"Grace DiGiovanni"},{"@type":"Person","name":"Daniel Millstein"},{"@type":"Person","name":"Kassandra Scioli"},{"@type":"Person","name":"Heidi DAurizio"},{"@type":"Person","name":"Lauren DeCaporale-Ryan"},{"@type":"Person","name":"Supriya Mohile"},{"@type":"Person","name":"Michelle Janelsins"},{"@type":"Person","name":"Robert J Ferguson"},{"@type":"Person","name":"Alissa Huston"},{"@type":"Person","name":"Allison Magnuson"}],"datePublished":"2026","isPartOf":{"@type":"Periodical","name":"JMIR formative research"},"identifier":"https://doi.org/10.2196/85140","description":"Abstract\n \n Background\n Cancer-related cognitive decline (CRCD) is a significant problem; interventions are needed to mitigate CRCD for older adults (aged ≥65 years).\n \n \n Objective\n Our objective was to develop and evaluate the usability of Memory and Attention Adaptation Training–Geriatrics (MAAT-G), a CRCD intervention for older adults with breast cancer undergoing systemic treatment.\n \n \n Methods\n We conducted an intervention adaptation study to develop MAAT-G. MAAT-G is a cognitive behavioral therapy–based intervention delivered by a health professional over the course of 10 weekly individual workshops via videoconferencing. To develop MAAT-G, the contextual, cohort-based, maturity, and specific challenge framework was used for preliminary adaptations. Patient advocate collaborators guided further refinement, reviewing MAAT-G workshop content, the participant workbook, and intervention delivery via videoconferencing to optimize relevance and usability for older adults. The usability of MAAT-G and its videoconferencing delivery were subsequently evaluated in 4 older adults with breast cancer using the System Usability Scale (score range 0‐100; >67 being above average) and through semistructured qualitative interviews.\n \n \n Results\n Numerous adaptations were made to address the unique needs of older patients using the contextual, cohort-based, maturity, and specific challenge framework and patient advocate feedback. Usability testing included 4 female patients with breast cancer (mean age 73.3, SD 3.77; range 67-77 years). Patients were receiving systemic therapy (2 receiving adjuvant therapy and 2 receiving advanced-stage disease therapy). One patient had an educational level lower than high school; 3 had some college education or higher. All 4 patients completed study procedures, including 10 MAAT-G workshop sessions (100% intervention adherence). The mean System Usability Scale score was 90.6 (SD 13.51), indicating good usability.\n \n \n Conclusions\n MAAT-G is a behavioral intervention developed to mitigate CRCD. It is designed specifically for older adults and showed above-average usability in this population.\n ","url":"https://innscience.ca/es/community/literature/doi_10_2196_85140"}